GW29-e1280 Renal denervation reduced ventricular arrhythmia post myocardial infarction and its potential mechanism
نویسندگان
چکیده
منابع مشابه
Effects of local cardiac denervation on cardiac innervation and ventricular arrhythmia after chronic myocardial infarction
BACKGROUND Modulation of the autonomic nervous system (ANS) has already been demonstrated to display antiarrhythmic effects in patients and animals with MI. In this study, we investigated whether local cardiac denervation has any beneficial effects on ventricular electrical stability and cardiac function in the chronic phase of MI. METHODS Twenty-one anesthetized dogs were randomly assigned i...
متن کاملPost-myocardial infarction mortality in patients with ventricular premature depolarizations. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Pilot Study.
BACKGROUND Among survivors of acute myocardial infarction, frequent and repetitive ventricular premature depolarizations (VPDs) detected on ambulatory monitoring contribute independently to the risk of all-cause mortality and sudden death. Apart from the beta-blockers, no antiarrhythmic drug has been reliably demonstrated to reduce mortality among patients with VPDs. A pilot study was undertake...
متن کاملRenal Sympathetic Denervation in Rats Ameliorates Cardiac Dysfunction and Fibrosis Post-Myocardial Infarction Involving MicroRNAs
BACKGROUND The role of renal sympathetic denervation (RSD) in ameliorating post-myocardial infarction (MI) left ventricular (LV) fibrosis via microRNA-dependent regulation of connective tissue growth factor (CTGF) remains unknown. MATERIAL AND METHODS MI and RSD were induced in Sprague-Dawley rats by ligating the left coronary artery and denervating the bilateral renal nerves, respectively. Nor...
متن کاملEffects of Renal Sympathetic Denervation on Post-Myocardial Infarction Cardiac Remodeling in Rats
OBJECTIVE To investigate the therapeutic effects of renal denervation (RD) on post- myocardial infarction (MI) cardiac remodeling in rats, the most optimal time for intervention and the sustainability of these effects. METHODS One hundred SPF male Wistar rats were randomly assigned to N group (Normal, n=10), MI group(MI, n=20),RD group (RD, n=10), RD3+MI (MI three days after RD, n=20), MI1+RD...
متن کامل[Post-myocardial infarction ventricular septal defect].
Post-myocardial infarction ventricular septal defect corresponds to the rupture of the ventricular septum between the healthy and infarcted parts. It is a rare complication still associated with a high mortality rate. Its diagnostic should be evoked in case of pathologic cardiac auscultation and confirmed by emergent transthoracic echocardiography. Hemodynamic stabilisation, mainly with the ins...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2018
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2018.08.146